Acido Ialuronico ExceptionHYAL® Jump

ExceptionHYAL® Jump Hyaluronic Acid is the Yamamoto Research supplement containing patented ExceptionHYAL® Jump Hyaluronic Acid, a biotechnological product belonging to a new generation of Hyaluronans, molecules that are essential for keeping our connective tissues well hydrated and healthy. This patent is characterised by a specific and selected spectrum of molecular weights, capable of performing anti-inflammatory and cartilage trophism activities, while exerting a lubricating and synovial fluid cushioning effect. ExceptionHYAL® Jump Hyaluronic Acid is the innovative solution** for promoting joint wellbeing and function during exercise and reducing and preventing the symptoms of osteoarthritis.

Hyaluronic acid is a molecule that is naturally present in the body. It is mainly found in the synovial fluid of the joints, where it exerts its action to allow all everyday movements while preventing or counteracting pain, because it acts as a shock absorber and lubricant. Indeed, it seems to be able to influence the way the body is able to react to injury. From a biological point of view, hyaluronic acid is a mucopolysaccharide, i.e. a molecule found in the fundamental substance of connective tissue and produced to hydrate and protect the tissues. Its distinctive characteristic is that it is able to bind with water molecules and retain them to create protective gels that are beneficial to the skin and joints. Due to its hydrating property, hyaluronic acid is essential for maintaining the firmness, viscosity and plasticity of connective tissue.

At skin level, it maintains the right degree of skin hydration, also exerting a replenishing action that allows the skin to maintain a young and relaxed appearance, while at joint level it acts as a mechanical shock absorber and lubricant, to protect the joints and cartilage from physical damage. The body’s natural hyaluronic acid content is influenced by the ageing process and the level of physical activity. As time goes by, the body’s production of hyaluronic acid tends to dwindle, a process that is accelerated by intense physical activity. Hyaluronic acid deficiency can make the joints prone to discomfort, problems and inflammation, which is why it is a good idea, especially for those who practise sport, to prevent these problems through proper supplementation of this molecule.

How can I provide the body with Hyaluronic Acid specifically intended for the joints?

ExceptionHYAL® Jump Hyaluronic Acid is produced using Full Spectrum Technlogy (HA Tech 2.0), a production method that guarantees the availability of a wide range of specific molecular weights. This process makes it possible, by means of biofermentation, to produce a complex of hyaluronans of different molecular weights without this being achieved by mixing individual molecular weights produced separately. Fine modulation of process parameters, including time and temperature, makes it possible to directly obtain specific spectra of sodium hyaluronate molecular weights for effective and targeted applications. This results in hyaluronic acid molecules able to integrate seamlessly into the biology of joint tissue, thus limiting pro-inflammatory processes and promoting cartilage trophism and a lubricating action in the synovial fluid, also through the synthesis of additional hyaluronic acid.

Hyaluronic Acid and joint support

Several in vitro and clinical studies have confirmed the effectiveness of hyaluronic acid supplementation in counteracting joint inflammation. Moreover, the intake of hyaluronic acid is considered safe and well tolerated.

The chondro-protective and lubricating function of the polymers contained in the patented product ExceptionHYAL® Jump can be used by sportsmen and women for joint support during exercise, but also for the more vulnerable population groups who need to maintain cartilage trophism.

Scientific references
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Kobayashi T, Chanmee T, Itano N. Hyaluronan: Metabolism and Function. Biomolecules. 2020 Nov 7;10(11):1525. doi: 10.3390/biom10111525. PMID: 33171800; PMCID: PMC7695009.

Balazs EA. Interaction between cells, hyaluronic acid and collagen. Ups J Med Sci. 1977;82(2):94. doi: 10.3109/03009737709179078. PMID: 20078294.

Hascall VC. Interaction of cartilage proteoglycans with hyaluronic acid. J Supramol Struct. 1977;7(1):101-20. doi: 10.1002/jss.400070110. PMID: 342830.

Camara CI, Bertocchi L, Ricci C, Bassi R, Bianchera A, Cantu’ L, Bettini R, Del Favero E. Hyaluronic Acid-Dexamethasone Nanoparticles for Local Adjunct Therapy of Lung Inflammation. Int J Mol Sci. 2021 Sep 28;22(19):10480. doi: 10.3390/ijms221910480. PMID: 34638821; PMCID: PMC8509068.

Deep dive report: Mobilizing the joint health category (2019) Natural Products Insider

Masi S (2020) The 2.0 Full Spectrum Hyaluronans Technology to improve bioavailability and efficacy performance. Agro Food Industry Hi-Tech 31(2), [www.teknoscienze.com/tksarticle/the-2-0-full-spectrum-hyaluronans-technology-to-improve-bioavailability-and-efficacy-performance-2/](http://www.teknoscienze.com/tks*article/the-2-0-full-spectrum-hyaluronans-technology-to-improve-bioavailability-and-efficacy-performance-2/)*

Cicero AFG, Girolimetto N, Bentivenga C et al (2020) Short-Term Effect of a New Oral Sodium Hyaluronate Formulation on Knee Osteoarthritis: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial. Diseases 8(3):26